As well as being a Depository for Federal Government information, R.M. Cooper Library is a Depository for South Carolina State Government Documents. The program is administered by the South Carolina State Library, which collects and distritutes documents published by South Carolina state agencies. Eleven libraries throughout the state participate in this program.

South Carolina Documents are housed on Level 3 of R.M. Cooper Library. Documents in this collection are arranged by South Carolina State Library call number, a unique classification system devised by the State Library. See the handout on Finding South Carolina Documents in the online catalog for more information. All items are listed in the Libraries' online catalog, and nearly everything is available to check out.